Scrivener + TextMate + Markdown
Chase Reeves and Dave Caolo each discuss how they're using these three tools together. Good stuff. Chase:
I’ve started writing all my notes in markdown because it’s so simple to get used to and can be converted to HTML in a click or two. I highly recommend getting familiar with markdown if your a blogger or digital note taker.
Dave:
. . . I’ve learned the hard way that composing blog posts in a browser is a bad idea. Unexpected crashes, network outages, etc. can destroy your hard work.